Dupuytren's Disease

23 Apr Dupuytren's Disease

Dupuytren's Disease is a rare connective tissue disorder characterized by the joints of some fingers (e.g., proximal interphalangeal joints and metacarpophalangeal joints) being permanently fixed in a flexible position (joint contractures). A hardened nodule may develop due to abnormal thickening and shortening of the bands of fibrous tissue under the skin of the palm (palmar fascia), eventually forming an abnormal band of hardened (fibrotic) tissue. As a result, the fingers of the affected area begin to retract towards the palm and cannot be retracted (contracture) for several months or years. Additionally, the skin of the affected area may shrink. In most cases, the ring and pinky (fourth and fifth) fingers are most affected. Additionally, the disorder usually affects both hands (bilateral). Although the exact cause of Dupuytren's contracture is unknown, the risk of the disease is increased by the presence or absence of certain other diseases, including alcoholic liver disease (cirrhosis) and diabetes, thyroid problems, and epilepsy. Additionally, it is thought that genetic predisposition may be a factor.

Dupuytren's symptoms

Dupuytren's contracture is characterized by the fingers being pulled towards the palm of the hand. Feet are rarely involved. Loss of function and deformities of the fingers, including nodular growths on the fingers, may also occur. One or both hands may be affected. When involvement is only unilateral (unilateral) the right hand appears to be involved more often. The ring finger is most commonly involved, followed by the little, middle and index fingers. A nodule or plaque may develop on the finger as the first symptom. Symptoms may develop spontaneously and without any known associated condition.

Dupuytren's Treatment

Dupuytren's disease is usually treated with corticosteroid injections into the affected tendon sheaths, analgesics for pain, and physical therapy. Surgery may be required depending on the size of the deformities. It is possible for it to relapse after surgery.